Decreased CD8(+ )T cell response to Epstein-Barr virus infected B cells in multiple sclerosis is not due to decreased HLA class I expression on B cells or monocytes

BACKGROUND: Patients with multiple sclerosis (MS) have a decreased frequency of CD8(+ )T cells reactive to their own Epstein-Barr virus (EBV) infected B cells. We have proposed that this might predispose to the development of MS by allowing EBV-infected autoreactive B cells to accumulate in the cent...

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Detalles Bibliográficos
Autores principales: Pender, Michael P, Csurhes, Peter A, Pfluger, Casey MM, Burrows, Scott R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163532/
https://www.ncbi.nlm.nih.gov/pubmed/21810280
http://dx.doi.org/10.1186/1471-2377-11-95

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163532/
https://www.ncbi.nlm.nih.gov/pubmed/21810280
http://dx.doi.org/10.1186/1471-2377-11-95

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