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Identification and Visualization of CD8(+) T Cell Mediated IFN-γ Signaling in Target Cells during an Antiviral Immune Response in the Brain

CD8(+) T cells infiltrate the brain during an anti-viral immune response. Within the brain CD8(+) T cells recognize cells expressing target antigens, become activated, and secrete IFNγ. However, there are no methods to recognize individual cells that respond to IFNγ. Using a model that studies the e...

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Detalles Bibliográficos
Autores principales: Puntel, Mariana, Barrett, Robert, Sanderson, Nicholas S. R., Kroeger, Kurt M., Bondale, Niyati, Wibowo, Mia, Kennedy, Sean, Liu, Chunyan, Castro, Maria G., Lowenstein, Pedro R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163574/
https://www.ncbi.nlm.nih.gov/pubmed/21897844
http://dx.doi.org/10.1371/journal.pone.0023523