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Identification and Visualization of CD8(+) T Cell Mediated IFN-γ Signaling in Target Cells during an Antiviral Immune Response in the Brain
CD8(+) T cells infiltrate the brain during an anti-viral immune response. Within the brain CD8(+) T cells recognize cells expressing target antigens, become activated, and secrete IFNγ. However, there are no methods to recognize individual cells that respond to IFNγ. Using a model that studies the e...
Autores principales: | Puntel, Mariana, Barrett, Robert, Sanderson, Nicholas S. R., Kroeger, Kurt M., Bondale, Niyati, Wibowo, Mia, Kennedy, Sean, Liu, Chunyan, Castro, Maria G., Lowenstein, Pedro R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163574/ https://www.ncbi.nlm.nih.gov/pubmed/21897844 http://dx.doi.org/10.1371/journal.pone.0023523 |
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