Germline Transgenic Pigs by Sleeping Beauty Transposition in Porcine Zygotes and Targeted Integration in the Pig Genome

Genetic engineering can expand the utility of pigs for modeling human diseases, and for developing advanced therapeutic approaches. However, the inefficient production of transgenic pigs represents a technological bottleneck. Here, we assessed the hyperactive Sleeping Beauty (SB100X) transposon syst...

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Detalles Bibliográficos
Autores principales: Garrels, Wiebke, Mátés, Lajos, Holler, Stephanie, Dalda, Anna, Taylor, Ulrike, Petersen, Björn, Niemann, Heiner, Izsvák, Zsuzsanna, Ivics, Zoltán, Kues, Wilfried A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163581/
https://www.ncbi.nlm.nih.gov/pubmed/21897845
http://dx.doi.org/10.1371/journal.pone.0023573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163581/
https://www.ncbi.nlm.nih.gov/pubmed/21897845
http://dx.doi.org/10.1371/journal.pone.0023573

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