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Integrin subunits alpha5 and alpha6 regulate cell cycle by modulating the chk1 and Rb/E2F pathways to affect breast cancer metastasis

BACKGROUND: Although integrins have been implicated in the progression of breast cancer, the exact mechanism whereby they exert this regulation is clearly not understood. To understand the role of integrins in breast cancer, we examined the expression levels of several integrins in mouse breast canc...

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Detalles Bibliográficos
Autores principales: Wang, Yanfang, Shenouda, Sylvia, Baranwal, Somesh, Rathinam, Rajamani, Jain, Prachi, Bao, Lili, Hazari, Siddhartha, Dash, Srikanta, Alahari, Suresh K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163626/
https://www.ncbi.nlm.nih.gov/pubmed/21752283
http://dx.doi.org/10.1186/1476-4598-10-84