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Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development
BACKGROUND: Plasmodium falciparum contains three genes encoding potential glutamate dehydrogenases. The protein encoded by gdha has previously been biochemically and structurally characterized. It was suggested that it is important for the supply of reducing equivalents during intra-erythrocytic dev...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163627/ https://www.ncbi.nlm.nih.gov/pubmed/21756354 http://dx.doi.org/10.1186/1475-2875-10-193 |