Dasatinib preferentially induces apoptosis by inhibiting Lyn kinase in nilotinib-resistant chronic myeloid leukemia cell line

Nilotinib is approved for treatment of newly diagnosed chronic myeloid leukemia (CML) and it is shown superiority over imatinib in first-line treatment for patients of CML. In this study, we established a nilotinib-resistant cell line, K562NR, and evaluated the resistance to nilotinib and efficacy o...

Descripción completa

Detalles Bibliográficos
Autores principales: Okabe, Seiichi, Tauchi, Tetsuzo, Tanaka, Yuko, Ohyashiki, Kazuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163636/
https://www.ncbi.nlm.nih.gov/pubmed/21806844
http://dx.doi.org/10.1186/1756-8722-4-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163636/
https://www.ncbi.nlm.nih.gov/pubmed/21806844
http://dx.doi.org/10.1186/1756-8722-4-32

Ejemplares similares