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BAFF Promotes Th17 Cells and Aggravates Experimental Autoimmune Encephalomyelitis

BACKGROUND: BAFF, in addition to promoting B cell survival and differentiation, may affect T cells. The objective of this study was to determine the effect of BAFF on Th17 cell generation and its ramifications for the Th17 cell-driven disease, EAE. METHODOLOGY/PRINCIPAL FINDINGS: Th17 cells were inc...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaohui, Xia, Zanxian, Lan, Qin, Wang, Julie, Su, Wenru, Han, Yuan-Ping, Fan, Huimin, Liu, Zhongmin, Stohl, William, Zheng, Song Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163640/
https://www.ncbi.nlm.nih.gov/pubmed/21897850
http://dx.doi.org/10.1371/journal.pone.0023629