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Profiling Trait Anxiety: Transcriptome Analysis Reveals Cathepsin B (Ctsb) as a Novel Candidate Gene for Emotionality in Mice

Behavioral endophenotypes are determined by a multitude of counteracting but precisely balanced molecular and physiological mechanisms. In this study, we aim to identify potential novel molecular targets that contribute to the multigenic trait “anxiety”. We used microarrays to investigate the gene e...

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Detalles Bibliográficos
Autores principales: Czibere, Ludwig, Baur, Laura A., Wittmann, Anke, Gemmeke, Katja, Steiner, Andrea, Weber, Peter, Pütz, Benno, Ahmad, Nafees, Bunck, Mirjam, Graf, Cornelia, Widner, Regina, Kühne, Claudia, Panhuysen, Markus, Hambsch, Boris, Rieder, Gabriele, Reinheckel, Thomas, Peters, Christoph, Holsboer, Florian, Landgraf, Rainer, Deussing, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163650/
https://www.ncbi.nlm.nih.gov/pubmed/21897848
http://dx.doi.org/10.1371/journal.pone.0023604