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Presence of RD149 Deletions in M. tuberculosis Central Asian Strain1 Isolates Affect Growth and TNFα Induction in THP-1 Monocytes

Central Asian Strain 1 (CAS1) is the prevalent Mycobacterium tuberculosis genogroup in South Asia. CAS1 strains carry deletions in RD149 and RD152 regions. Significance of these deletions is as yet unknown. We compared CAS1 strains with RD149 and concurrent RD149-RD152 deletions with CAS1 strains wi...

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Detalles Bibliográficos
Autores principales: Kanji, Akbar, Hasan, Zahra, Tanveer, Mehnaz, Mahboob, Raunaq, Jafri, Sana, Hasan, Rumina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163664/
https://www.ncbi.nlm.nih.gov/pubmed/21904612
http://dx.doi.org/10.1371/journal.pone.0024178