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An epitope conserved in orthopoxvirus A13 envelope protein is the target of neutralizing and protective antibodies

Primary immunization of humans with smallpox vaccine (live vaccinia virus (VACV)) consistently elicits antibody responses to six VACV virion membrane proteins, including A13. However, whether anti-A13 antibody contributes to immune protection against orthopoxviruses was unknown. Here, we isolated a...

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Detalles Bibliográficos
Autores principales: Xu, Chungui, Meng, Xiangzhi, Yan, Bo, Crotty, Shane, Deng, Junpeng, Xiang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163717/
https://www.ncbi.nlm.nih.gov/pubmed/21810533
http://dx.doi.org/10.1016/j.virol.2011.06.029