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An epitope conserved in orthopoxvirus A13 envelope protein is the target of neutralizing and protective antibodies
Primary immunization of humans with smallpox vaccine (live vaccinia virus (VACV)) consistently elicits antibody responses to six VACV virion membrane proteins, including A13. However, whether anti-A13 antibody contributes to immune protection against orthopoxviruses was unknown. Here, we isolated a...
Autores principales: | Xu, Chungui, Meng, Xiangzhi, Yan, Bo, Crotty, Shane, Deng, Junpeng, Xiang, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163717/ https://www.ncbi.nlm.nih.gov/pubmed/21810533 http://dx.doi.org/10.1016/j.virol.2011.06.029 |
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