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MicroRNAs can generate thresholds in target gene expression
MicroRNAs (miRNAs) are short, highly conserved non-coding RNA molecules that repress gene expression in a sequence-dependent manner. We performed single-cell measurements using quantitative fluorescence microscopy and flow cytometry to monitor a target gene’s protein expression in the presence and a...
Autores principales: | Mukherji, Shankar, Ebert, Margaret S., Zheng, Grace X., Tsang, John S., Sharp, Phillip A., van Oudenaarden, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163764/ https://www.ncbi.nlm.nih.gov/pubmed/21857679 http://dx.doi.org/10.1038/ng.905 |
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