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Insights from the analysis of conserved motifs and permitted amino acid exchanges in the human, the fly and the worm GPCR clusters

G-protein coupled receptors (GPCRs) belong to biologically important and functionally diverse and largest super family of membrane proteins. GPCRs retain a characteristic membrane topology of seven alpha helices with three intracellular, three extracellular loops and flanking N' and C' ter...

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Detalles Bibliográficos
Autores principales: Nagarathnam, Balasubramanian, Kannan, Sankar, Dharnidharka, Varadhan, Balakrishnan, Veluchamy, Archunan, Govindaraju, Sowdhamini, Ramanathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163927/
https://www.ncbi.nlm.nih.gov/pubmed/21904433