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Dot/Icm Type IVB Secretion System Requirements for Coxiella burnetii Growth in Human Macrophages
Central to Q fever pathogenesis is replication of the causative agent, Coxiella burnetii, within a phagolysosome-like parasitophorous vacuole (PV) in mononuclear phagocytes. C. burnetii modulates PV biogenesis and other host cell functions, such as apoptotic signaling, presumably via the activity of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163939/ https://www.ncbi.nlm.nih.gov/pubmed/21862628 http://dx.doi.org/10.1128/mBio.00175-11 |