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Fragile x syndrome and autism: from disease model to therapeutic targets

Autism is an umbrella diagnosis with several different etiologies. Fragile X syndrome (FXS), one of the first identified and leading causes of autism, has been modeled in mice using molecular genetic manipulation. These Fmr1 knockout mice have recently been used to identify a new putative therapeuti...

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Detalles Bibliográficos
Autores principales: Dölen, Gül, Bear, Mark F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164025/
https://www.ncbi.nlm.nih.gov/pubmed/21547712
http://dx.doi.org/10.1007/s11689-009-9015-x