Biological Activity of CXCL8 Forms Generated by Alternative Cleavage of the Signal Peptide or by Aminopeptidase-Mediated Truncation

BACKGROUND: Posttranslational modification of chemokines is one of the mechanisms that regulate leukocyte migration during inflammation. Multiple natural NH(2)-terminally truncated forms of the major human neutrophil attractant interleukin-8 or CXCL8 have been identified. Although differential activ...

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Detalles Bibliográficos
Autores principales: Mortier, Anneleen, Berghmans, Nele, Ronsse, Isabelle, Grauwen, Karolien, Stegen, Steve, Van Damme, Jo, Proost, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164136/
https://www.ncbi.nlm.nih.gov/pubmed/21904597
http://dx.doi.org/10.1371/journal.pone.0023913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164136/
https://www.ncbi.nlm.nih.gov/pubmed/21904597
http://dx.doi.org/10.1371/journal.pone.0023913

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