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Fragmentation of Contaminant and Endogenous DNA in Ancient Samples Determined by Shotgun Sequencing; Prospects for Human Palaeogenomics

BACKGROUND: Despite the successful retrieval of genomes from past remains, the prospects for human palaeogenomics remain unclear because of the difficulty of distinguishing contaminant from endogenous DNA sequences. Previous sequence data generated on high-throughput sequencing platforms indicate th...

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Detalles Bibliográficos
Autores principales: García-Garcerà, Marc, Gigli, Elena, Sanchez-Quinto, Federico, Ramirez, Oscar, Calafell, Francesc, Civit, Sergi, Lalueza-Fox, Carles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164143/
https://www.ncbi.nlm.nih.gov/pubmed/21904610
http://dx.doi.org/10.1371/journal.pone.0024161