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Structural Mechanism of S-Adenosyl Methionine Binding to Catechol O-Methyltransferase
Methyltransferases possess a homologous domain that requires both a divalent metal cation and S-adenosyl-L-methionine (SAM) to catalyze its reactions. The kinetics of several methyltransferases has been well characterized; however, the details regarding their structural mechanisms have remained uncl...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164188/ https://www.ncbi.nlm.nih.gov/pubmed/21904625 http://dx.doi.org/10.1371/journal.pone.0024287 |