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SVIP Induces Localization of p97/VCP to the Plasma and Lysosomal Membranes and Regulates Autophagy

The small p97/VCP-interacting protein (SVIP) functions as an inhibitor of the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Here we show that overexpression of SVIP in HeLa cells leads to localization of p97/VCP at the plasma membrane, intracellular foci and juxtanuclear vacuoles...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Ballar, Petek, Zhong, Yongwang, Zhang, Xuebao, Liu, Chao, Zhang, Ying-Jiu, Monteiro, Mervyn J., Li, Jun, Fang, Shengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164199/
https://www.ncbi.nlm.nih.gov/pubmed/21909394
http://dx.doi.org/10.1371/journal.pone.0024478