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No Evidence for Strong Recent Positive Selection Favoring the 7 Repeat Allele of VNTR in the DRD4 Gene

The human dopamine receptor D4 (DRD4) gene contains a 48-bp variable number of tandem repeat (VNTR) in exon 3, encoding the third intracellular loop of this dopamine receptor. The DRD4 7R allele, which seems to have a single origin, is commonly observed in various human populations and the nucleotid...

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Detalles Bibliográficos
Autores principales: Naka, Izumi, Nishida, Nao, Ohashi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164202/
https://www.ncbi.nlm.nih.gov/pubmed/21909391
http://dx.doi.org/10.1371/journal.pone.0024410