Molecular Insights into Reprogramming-Initiation Events Mediated by the OSKM Gene Regulatory Network

Somatic cells can be reprogrammed to induced pluripotent stem cells by over-expression of OCT4, SOX2, KLF4 and c-MYC (OSKM). With the aim of unveiling the early mechanisms underlying the induction of pluripotency, we have analyzed transcriptional profiles at 24, 48 and 72 hours post-transduction of...

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Detalles Bibliográficos
Autores principales: Mah, Nancy, Wang, Ying, Liao, Mei-Chih, Prigione, Alessandro, Jozefczuk, Justyna, Lichtner, Björn, Wolfrum, Katharina, Haltmeier, Manuela, Flöttmann, Max, Schaefer, Martin, Hahn, Alexander, Mrowka, Ralf, Klipp, Edda, Andrade-Navarro, Miguel A., Adjaye, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164204/
https://www.ncbi.nlm.nih.gov/pubmed/21909390
http://dx.doi.org/10.1371/journal.pone.0024351

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164204/
https://www.ncbi.nlm.nih.gov/pubmed/21909390
http://dx.doi.org/10.1371/journal.pone.0024351

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