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Defective Fluid Secretion from Submucosal Glands of Nasal Turbinates from CFTR(-/-) and CFTR(ΔF508/ΔF508) Pigs

BACKGROUND: Cystic fibrosis (CF), caused by reduced CFTR function, includes severe sinonasal disease which may predispose to lung disease. Newly developed CF pigs provide models to study the onset of CF pathophysiology. We asked if glands from pig nasal turbinates have secretory responses similar to...

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Detalles Bibliográficos
Autores principales: Cho, Hyung-Ju, Joo, Nam Soo, Wine, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164206/
https://www.ncbi.nlm.nih.gov/pubmed/21935358
http://dx.doi.org/10.1371/journal.pone.0024424