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Control of the Intracellular Redox State by Glucose Participates in the Insulin Secretion Mechanism

BACKGROUND: Production of reactive oxygen species (ROS) due to chronic exposure to glucose has been associated with impaired beta cell function and diabetes. However, physiologically, beta cells are well equipped to deal with episodic glucose loads, to which they respond with a fine tuned glucose-st...

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Detalles Bibliográficos
Autores principales: Rebelato, Eduardo, Abdulkader, Fernando, Curi, Rui, Carpinelli, Angelo Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164208/
https://www.ncbi.nlm.nih.gov/pubmed/21909396
http://dx.doi.org/10.1371/journal.pone.0024507