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Control of the Intracellular Redox State by Glucose Participates in the Insulin Secretion Mechanism
BACKGROUND: Production of reactive oxygen species (ROS) due to chronic exposure to glucose has been associated with impaired beta cell function and diabetes. However, physiologically, beta cells are well equipped to deal with episodic glucose loads, to which they respond with a fine tuned glucose-st...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164208/ https://www.ncbi.nlm.nih.gov/pubmed/21909396 http://dx.doi.org/10.1371/journal.pone.0024507 |