Cargando…

Control of the Intracellular Redox State by Glucose Participates in the Insulin Secretion Mechanism

BACKGROUND: Production of reactive oxygen species (ROS) due to chronic exposure to glucose has been associated with impaired beta cell function and diabetes. However, physiologically, beta cells are well equipped to deal with episodic glucose loads, to which they respond with a fine tuned glucose-st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rebelato, Eduardo, Abdulkader, Fernando, Curi, Rui, Carpinelli, Angelo Rafael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164208/ https://www.ncbi.nlm.nih.gov/pubmed/21909396 http://dx.doi.org/10.1371/journal.pone.0024507

Ejemplares similares

Short-term high glucose culture potentiates pancreatic beta cell function
por: Rebelato, Eduardo, et al.
Publicado: (2018)

Control of Insulin Secretion by Production of Reactive Oxygen Species: Study Performed in Pancreatic Islets from Fed and 48-Hour Fasted Wistar Rats
por: Munhoz, Ana Cláudia, et al.
Publicado: (2016)

Maternal Moderate Physical Training during Pregnancy Attenuates the Effects of a Low-Protein Diet on the Impaired Secretion of Insulin in Rats: Potential Role for Compensation of Insulin Resistance and Preventing Gestational Diabetes Mellitus
por: Leandro, Carol Góis, et al.
Publicado: (2012)

Regional Variations of Insulin Secretion and Insulin Sensitivity in Japanese Participants With Normal Glucose Tolerance
por: Watanabe, Kiriko, et al.
Publicado: (2021)

DHEA supplementation in ovariectomized rats reduces impaired glucose-stimulated insulin secretion induced by a high-fat diet()
por: Veras, Katherine, et al.
Publicado: (2014)

Geniposide Balances the Redox Signaling to Mediate Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells
por: Liu, Chunyan, et al.
Publicado: (2020)

Zinc Supplementation Improves Glucose Homeostasis in High Fat-Fed Mice by Enhancing Pancreatic β-Cell Function
por: Cooper-Capetini, Vinícius, et al.
Publicado: (2017)

Rising Intracellular Zinc by Membrane Depolarization and Glucose in Insulin-Secreting Clonal HIT-T15 Beta Cells
por: Slepchenko, Kira G., et al.
Publicado: (2012)

RGS4-Deficiency Alters Intracellular Calcium and PKA-Mediated Control of Insulin Secretion in Glucose-Stimulated Beta Islets
por: Bastin, Guillaume, et al.
Publicado: (2021)

Hypothalamic Regulation of Glucose-Stimulated Insulin Secretion
por: Chan, Owen, et al.
Publicado: (2012)

Insulin Augmentation of Glucose-Stimulated Insulin Secretion Is Impaired in Insulin-Resistant Humans
por: Halperin, Florencia, et al.
Publicado: (2012)

Deletion of GPR40 Impairs Glucose-Induced Insulin Secretion In Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets
por: Alquier, Thierry, et al.
Publicado: (2009)

Role of Vitamin D in Insulin Secretion and Insulin Sensitivity for Glucose Homeostasis
por: Alvarez, Jessica A., et al.
Publicado: (2010)

Data on intracellular localization of RPSA upon alteration of its redox state
por: Vilas-Boas, Filipe, et al.
Publicado: (2015)

Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion
por: Sacco, Francesca, et al.
Publicado: (2016)

Telomerase deficiency impairs glucose metabolism and insulin secretion
por: Kuhlow, Doreen, et al.
Publicado: (2010)

Glucose‐stimulated insulin secretion: A newer perspective
por: Komatsu, Mitsuhisa, et al.
Publicado: (2013)

Effects of Type 2 Diabetes on Insulin Secretion, Insulin Action, Glucose Effectiveness, and Postprandial Glucose Metabolism
por: Basu, Ananda, et al.
Publicado: (2009)

Overexpression of the transcription factor Yap1 modifies intracellular redox conditions and enhances recombinant protein secretion
por: Delic, Marizela, et al.
Publicado: (2014)

Inferring Insulin Secretion Rate from Sparse Patient Glucose and Insulin Measures
por: Abohtyra, Rammah M., et al.
Publicado: (2022)

Intracellular Redox State as Target for Anti-Influenza Therapy: Are Antioxidants Always Effective?
por: Sgarbanti, Rossella, et al.
Publicado: (2014)

α-cell electrophysiology and the regulation of glucagon secretion
por: Gao, Rui, et al.
Publicado: (2023)

Aging Affects Insulin Resistance, Insulin Secretion, and Glucose Effectiveness in Subjects with Normal Blood Glucose and Body Weight
por: Huang, Li-Ying, et al.
Publicado: (2023)

Notoginsenoside R1 attenuates high glucose-induced endothelial damage in rat retinal capillary endothelial cells by modulating the intracellular redox state
por: Fan, Chunlan, et al.
Publicado: (2017)

Partial Inhibition of Insulin Secretion Results in Glucose Intolerance but Not Hyperglucagonemia
por: Ramanathan, Ranjani P., et al.
Publicado: (2011)

ADCY5 Couples Glucose to Insulin Secretion in Human Islets
por: Hodson, David J., et al.
Publicado: (2014)

LPS-Enhanced Glucose-Stimulated Insulin Secretion Is Normalized by Resveratrol
por: Nøhr, Mark K., et al.
Publicado: (2016)

Modeling the effect of the cephalic phase of insulin secretion on glucose metabolism
por: Güemes, Amparo, et al.
Publicado: (2019)

α-Synuclein Regulates Peripheral Insulin Secretion and Glucose Transport
por: Wijesekara, Nadeeja, et al.
Publicado: (2021)

The role of glucose and insulin in the metabolic regulation of growth hormone secretion
por: Sorkina, E. L., et al.
Publicado: (2021)

Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms
por: Panse, Madhura, et al.
Publicado: (2018)

Intracellular Redox-Balance Involvement in Temozolomide Resistance-Related Molecular Mechanisms in Glioblastoma
por: Lo Dico, Alessia, et al.
Publicado: (2019)

Ghrelin Suppresses Glucose-Stimulated Insulin Secretion and Deteriorates Glucose Tolerance in Healthy Humans
por: Tong, Jenny, et al.
Publicado: (2010)

Systematic Synergy of Glucose and GLP-1 to Stimulate Insulin Secretion Revealed by Quantitative Phosphoproteomics
por: Tang, Jia-shu, et al.
Publicado: (2017)

Closing in on the Mechanisms of Pulsatile Insulin Secretion
por: Bertram, Richard, et al.
Publicado: (2018)

Relationship between serum adipsin and the first phase of glucose‐stimulated insulin secretion in individuals with different glucose tolerance
por: Zhou, Qing, et al.
Publicado: (2018)

Nutrient-stimulated insulin secretion in mouse islets is critically dependent on intracellular pH
por: Gunawardana, Subhadra C, et al.
Publicado: (2004)

Intracellular Serotonin Modulates Insulin Secretion from Pancreatic β-Cells by Protein Serotonylation
por: Paulmann, Nils, et al.
Publicado: (2009)

GLP-1 receptor activated insulin secretion from pancreatic β-cells: mechanism and glucose dependence
por: Meloni, A R, et al.
Publicado: (2013)

Assessment of endogenous insulin secretion in insulin treated diabetes predicts postprandial glucose and treatment response to prandial insulin
por: Jones, Angus G, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_h3g0gkd2ok4t3stp17d30356or