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JNK2 Promotes Endothelial Cell Alignment under Flow

Endothelial cells in straight, unbranched segments of arteries elongate and align in the direction of flow, a feature which is highly correlated with reduced atherosclerosis in these regions. The mitogen-activated protein kinase c-Jun N-terminal kinase (JNK) is activated by flow and is linked to inf...

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Detalles Bibliográficos
Autores principales: Hahn, Cornelia, Wang, Chong, Orr, A. Wayne, Coon, Brian G., Schwartz, Martin Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164210/
https://www.ncbi.nlm.nih.gov/pubmed/21909388
http://dx.doi.org/10.1371/journal.pone.0024338