Feedback inhibition of L1 and alu retrotransposition through altered double strand break repair kinetics

BACKGROUND: Cells adapt to various chronic toxic exposures in a multitude of ways to minimize further damage and maximize their growth potential. Expression of L1 elements in the human genome can be greatly deleterious to cells, generating numerous double strand breaks (DSBs). Cells have been report...

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Detalles Bibliográficos
Autores principales: Wallace, Nicholas A, Belancio, Victoria P, Faber, Zach, Deininger, Prescott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164224/
https://www.ncbi.nlm.nih.gov/pubmed/20979631
http://dx.doi.org/10.1186/1759-8753-1-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164224/
https://www.ncbi.nlm.nih.gov/pubmed/20979631
http://dx.doi.org/10.1186/1759-8753-1-22

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