The nuclear envelope localization of DYT1 dystonia torsinA-ΔE requires the SUN1 LINC complex component

BACKGROUND: DYT1 dystonia is an autosomal dominant neurological condition caused by a mutation that removes a single glutamic acid residue (ΔE) from the torsinA (torA) AAA+ protein. TorA appears to possess a nuclear envelope (NE) localized activity that requires Lamina-Associated-Polypeptide 1 (LAP1...

Descripción completa

Detalles Bibliográficos
Autores principales: Jungwirth, Michael T, Kumar, Dhivya, Jeong, Danielle Y, Goodchild, Rose E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164226/
https://www.ncbi.nlm.nih.gov/pubmed/21627841
http://dx.doi.org/10.1186/1471-2121-12-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164226/
https://www.ncbi.nlm.nih.gov/pubmed/21627841
http://dx.doi.org/10.1186/1471-2121-12-24

Ejemplares similares