Induction of Innate Immune Responses by SIV In Vivo and In Vitro: Differential Expression and Function of RIG-I and MDA5

Interferon-β induction occurs during acute simian immunodeficiency virus (SIV) infection in the brain. We have examined expression and function of cytosolic RNA sensors, retinoic acid inducible gene I (RIG-I), and melanoma differentiation-associated protein 5 (MDA5), in vivo in the brain of our cons...

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Detalles Bibliográficos
Autores principales: Co, Juliene G., Witwer, Kenneth W., Gama, Lucio, Zink, M. Christine, Clements, Janice E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164431/
https://www.ncbi.nlm.nih.gov/pubmed/21881126
http://dx.doi.org/10.1093/infdis/jir469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164431/
https://www.ncbi.nlm.nih.gov/pubmed/21881126
http://dx.doi.org/10.1093/infdis/jir469

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