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Induction of Innate Immune Responses by SIV In Vivo and In Vitro: Differential Expression and Function of RIG-I and MDA5

Interferon-β induction occurs during acute simian immunodeficiency virus (SIV) infection in the brain. We have examined expression and function of cytosolic RNA sensors, retinoic acid inducible gene I (RIG-I), and melanoma differentiation-associated protein 5 (MDA5), in vivo in the brain of our cons...

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Detalles Bibliográficos
Autores principales:	Co, Juliene G., Witwer, Kenneth W., Gama, Lucio, Zink, M. Christine, Clements, Janice E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Major Articles and Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164431/ https://www.ncbi.nlm.nih.gov/pubmed/21881126 http://dx.doi.org/10.1093/infdis/jir469

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