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Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells

Coxsackievirus B (CVB), a member of the enterovirus family, targets the polarized epithelial cells lining the intestinal tract early in infection. Although the polarized epithelium functions as a protective barrier, this barrier is likely exploited by CVB to promote viral entry and subsequent egress...

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Detalles Bibliográficos
Autores principales: Bozym, Rebecca A., Patel, Kunal, White, Carl, Cheung, King-Ho, Bergelson, Jeffrey M., Morosky, Stefanie A., Coyne, Carolyn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164450/
https://www.ncbi.nlm.nih.gov/pubmed/21737691
http://dx.doi.org/10.1091/mbc.E11-02-0094