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Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogaster
In metazoans, the highly conserved Notch pathway drives cellular specification. On receptor activation, the intracellular domain of Notch assembles a transcriptional activator complex that includes the DNA-binding protein CSL, a composite of human C-promoter binding factor 1, Suppressor of Hairless...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164469/ https://www.ncbi.nlm.nih.gov/pubmed/21737682 http://dx.doi.org/10.1091/mbc.E11-05-0420 |