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Structural and functional analysis of the repressor complex in the Notch signaling pathway of Drosophila melanogaster

In metazoans, the highly conserved Notch pathway drives cellular specification. On receptor activation, the intracellular domain of Notch assembles a transcriptional activator complex that includes the DNA-binding protein CSL, a composite of human C-promoter binding factor 1, Suppressor of Hairless...

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Detalles Bibliográficos
Autores principales: Maier, Dieter, Kurth, Patricia, Schulz, Adriana, Russell, Andrew, Yuan, Zhenyu, Gruber, Kim, Kovall, Rhett A., Preiss, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164469/
https://www.ncbi.nlm.nih.gov/pubmed/21737682
http://dx.doi.org/10.1091/mbc.E11-05-0420