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RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis

RhoGTPases are key signaling molecules regulating main cellular functions such as migration, proliferation, survival, and gene expression through interactions with various effectors. Within the RhoA-related subclass, RhoA and RhoC contribute to several steps of tumor growth, and the regulation of th...

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Detalles Bibliográficos
Autores principales: Giang Ho, T. T., Stultiens, Audrey, Dubail, Johanne, Lapière, Charles M., Nusgens, Betty V., Colige, Alain C., Deroanne, Christophe F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164471/
https://www.ncbi.nlm.nih.gov/pubmed/21757538
http://dx.doi.org/10.1091/mbc.E11-01-0020