Constitutive and Chemokine-dependent Internalization and Recycling of CXCR7 in Breast Cancer Cells to Degrade Chemokine Ligands

CXCR7 is a receptor for chemokines including CXCL12 (SDF-1), a molecule that promotes tumor growth and metastasis in breast cancer and other malignancies. Building upon the recent observation that CXCR7 sequesters CXCL12, we investigated mechanisms for CXCR7-dependent uptake of chemokines. Breast ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Luker, Kathryn E., Steele, Jessica M., Mihalko, Laura Anne, Ray, Paramita, Luker, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164491/
https://www.ncbi.nlm.nih.gov/pubmed/20531309
http://dx.doi.org/10.1038/onc.2010.212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164491/
https://www.ncbi.nlm.nih.gov/pubmed/20531309
http://dx.doi.org/10.1038/onc.2010.212

Ejemplares similares