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Role of epithelial integrin-linked kinase in promoting intestinal inflammation: effects on CCL2, fibronectin and the T cell repertoire

BACKGROUND: The role of integrin signaling in mucosal inflammation is presently unknown. Hence, we aimed to investigate the role of epithelial-derived integrin-linked kinase (ILK), a critical integrin signaling intermediary molecule, in colonic inflammation. METHODS: Conditional intestinal epithelia...

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Detalles Bibliográficos
Autores principales: Assi, Kiran, Patterson, Scott, Dedhar, Shoukat, Owen, David, Levings, Megan, Salh, Baljinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164617/
https://www.ncbi.nlm.nih.gov/pubmed/21806815
http://dx.doi.org/10.1186/1471-2172-12-42