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ZEB1 limits adenoviral infectability by transcriptionally repressing the Coxsackie virus and Adenovirus Receptor

BACKGROUND: We have previously reported that RAS-MEK (Cancer Res. 2003 May 1;63(9):2088-95) and TGF-β (Cancer Res. 2006 Feb 1;66(3):1648-57) signaling negatively regulate coxsackie virus and adenovirus receptor (CAR) cell-surface expression and adenovirus uptake. In the case of TGF-β, down-regulatio...

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Detalles Bibliográficos
Autores principales: Lacher, Markus D, Shiina, Marisa, Chang, Peter, Keller, Debora, Tiirikainen, Maarit I, Korn, W Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164624/
https://www.ncbi.nlm.nih.gov/pubmed/21791114
http://dx.doi.org/10.1186/1476-4598-10-91