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Chlamydia trachomatis Co-opts GBF1 and CERT to Acquire Host Sphingomyelin for Distinct Roles during Intracellular Development
The obligate intracellular pathogen Chlamydia trachomatis replicates within a membrane-bound inclusion that acquires host sphingomyelin (SM), a process that is essential for replication as well as inclusion biogenesis. Previous studies demonstrate that SM is acquired by a Brefeldin A (BFA)-sensitive...
Autores principales: | Elwell, Cherilyn A., Jiang, Shaobo, Kim, Jung Hwa, Lee, Albert, Wittmann, Torsten, Hanada, Kentaro, Melancon, Paul, Engel, Joanne N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164637/ https://www.ncbi.nlm.nih.gov/pubmed/21909260 http://dx.doi.org/10.1371/journal.ppat.1002198 |
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