PfMDR1: Mechanisms of Transport Modulation by Functional Polymorphisms

ATP-Binding Cassette (ABC) transporters are efflux pumps frequently associated with multidrug resistance in many biological systems, including malaria. Antimalarial drug-resistance involves an ABC transporter, PfMDR1, a homologue of P-glycoprotein in humans. Twenty years of research have shown that...

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Detalles Bibliográficos
Autores principales: Ferreira, Pedro Eduardo, Holmgren, Gabrielle, Veiga, Maria Isabel, Uhlén, Per, Kaneko, Akira, Gil, José Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164660/
https://www.ncbi.nlm.nih.gov/pubmed/21912647
http://dx.doi.org/10.1371/journal.pone.0023875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164660/
https://www.ncbi.nlm.nih.gov/pubmed/21912647
http://dx.doi.org/10.1371/journal.pone.0023875

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