The 4C5 Cell-Impermeable Anti-HSP90 Antibody with Anti-Cancer Activity, Is Composed of a Single Light Chain Dimer

MAb 4C5 is a cell impermeable, anti-HSP90 murine monoclonal antibody, originally produced using hybridoma technology. We have previously shown that mAb 4C5 specifically recognizes both the α- and to a lesser extent the β-isoform of HSP90. Additionally, in vitro and in vivo studies revealed that by s...

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Detalles Bibliográficos
Autores principales: Sidera, Katerina, El Hamidieh, Avraam, Mamalaki, Avgi, Patsavoudi, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164667/
https://www.ncbi.nlm.nih.gov/pubmed/21912649
http://dx.doi.org/10.1371/journal.pone.0023906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164667/
https://www.ncbi.nlm.nih.gov/pubmed/21912649
http://dx.doi.org/10.1371/journal.pone.0023906

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