Systemic Immune Activation in HIV Infection Is Associated with Decreased MDC Responsiveness to TLR Ligand and Inability to Activate Naive CD4 T-Cells

BACKGROUND: HIV infection is characterized by ineffective anti-viral T-cell responses and impaired dendritic cell (DC) functions, including response to Toll-Like Receptor (TLR) ligands. Because TLR responsiveness may affect a host's response to virus, we examined TLR ligand induced Myeloid and...

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Detalles Bibliográficos
Autores principales: Yonkers, Nicole L., Rodriguez, Benigno, Asaad, Robert, Lederman, Michael M., Anthony, Donald D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164669/
https://www.ncbi.nlm.nih.gov/pubmed/21912648
http://dx.doi.org/10.1371/journal.pone.0023884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164669/
https://www.ncbi.nlm.nih.gov/pubmed/21912648
http://dx.doi.org/10.1371/journal.pone.0023884

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