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Genome-Wide Identification of Bcl11b Gene Targets Reveals Role in Brain-Derived Neurotrophic Factor Signaling

B-cell leukemia/lymphoma 11B (Bcl11b) is a transcription factor showing predominant expression in the striatum. To date, there are no known gene targets of Bcl11b in the nervous system. Here, we define targets for Bcl11b in striatal cells by performing chromatin immunoprecipitation followed by high-...

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Detalles Bibliográficos
Autores principales: Tang, Bin, Di Lena, Pietro, Schaffer, Lana, Head, Steven R., Baldi, Pierre, Thomas, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164671/
https://www.ncbi.nlm.nih.gov/pubmed/21912641
http://dx.doi.org/10.1371/journal.pone.0023691