Novel Aptamer-Nanoparticle Bioconjugates Enhances Delivery of Anticancer Drug to MUC1-Positive Cancer Cells In Vitro

MUC1 protein is an attractive target for anticancer drug delivery owing to its overexpression in most adenocarcinomas. In this study, a reported MUC1 protein aptamer is exploited as the targeting agent of a nanoparticle-based drug delivery system. Paclitaxel (PTX) loaded poly (lactic-co-glycolic-aci...

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Detalles Bibliográficos
Autores principales: Yu, Chenchen, Hu, Yan, Duan, Jinhong, Yuan, Wei, Wang, Chen, Xu, Haiyan, Yang, Xian-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164674/
https://www.ncbi.nlm.nih.gov/pubmed/21912664
http://dx.doi.org/10.1371/journal.pone.0024077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164674/
https://www.ncbi.nlm.nih.gov/pubmed/21912664
http://dx.doi.org/10.1371/journal.pone.0024077

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