Cargando…

Novel Aptamer-Nanoparticle Bioconjugates Enhances Delivery of Anticancer Drug to MUC1-Positive Cancer Cells In Vitro

MUC1 protein is an attractive target for anticancer drug delivery owing to its overexpression in most adenocarcinomas. In this study, a reported MUC1 protein aptamer is exploited as the targeting agent of a nanoparticle-based drug delivery system. Paclitaxel (PTX) loaded poly (lactic-co-glycolic-aci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Chenchen, Hu, Yan, Duan, Jinhong, Yuan, Wei, Wang, Chen, Xu, Haiyan, Yang, Xian-Da
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164674/ https://www.ncbi.nlm.nih.gov/pubmed/21912664 http://dx.doi.org/10.1371/journal.pone.0024077

Ejemplares similares

Aptamer-guided DNA tetrahedron as a novel targeted drug delivery system for MUC1-expressing breast cancer cells in vitro
por: Dai, Bindong, et al.
Publicado: (2016)

Novel Bispecific Aptamer Enhances Immune Cytotoxicity Against MUC1-Positive Tumor Cells by MUC1-CD16 Dual Targeting
por: Li, Zhaoyi, et al.
Publicado: (2019)

Novel MUC1 Aptamer Selectively Delivers Cytotoxic Agent to Cancer Cells In Vitro
por: Hu, Yan, et al.
Publicado: (2012)

Bioconjugate-loaded solid lipid nanoparticles for enhanced anticancer drug delivery to brain cancer cells: An in vitro evaluation
por: Jain, Priyanka, et al.
Publicado: (2022)

Dendrimer– and polymeric nanoparticle–aptamer bioconjugates as nonviral delivery systems: a new approach in medicine
por: Mignani, Serge, et al.
Publicado: (2020)

Targeted Delivery of Sunitinib by MUC-1 Aptamer-Capped Magnetic Mesoporous Silica Nanoparticles
por: Torabi, Mitra, et al.
Publicado: (2023)

Targeted Treatment of Colon Cancer with Aptamer-Guided Albumin Nanoparticles Loaded with Docetaxel
por: Yu, Zhen, et al.
Publicado: (2020)

Selection of a novel CD19 aptamer for targeted delivery of doxorubicin to lymphoma cells
por: Hu, Yan, et al.
Publicado: (2018)

Aptamer-Gated Nanoparticles for Smart Drug Delivery
por: Ozalp, Veli Cengiz, et al.
Publicado: (2011)

Polydopamine-Based Surface Modification of Novel Nanoparticle-Aptamer Bioconjugates for In Vivo Breast Cancer Targeting and Enhanced Therapeutic Effects
por: Tao, Wei, et al.
Publicado: (2016)

Turning an Aptamer into a Light-Switch Probe with a Single Bioconjugation
por: Wickramaratne, Thakshila M., et al.
Publicado: (2014)

Current Aspects of siRNA Bioconjugate for In Vitro and In Vivo Delivery
por: Tai, Wanyi
Publicado: (2019)

Codelivery of Genistein and miRNA-29b to A549 Cells Using Aptamer-Hybrid Nanoparticle Bioconjugates
por: Sacko, Koita, et al.
Publicado: (2019)

Towards potent but less toxic nanopharmaceuticals – lipoic acid bioconjugates of ultrasmall gold nanoparticles with an anticancer drug and addressing unit
por: Dzwonek, Maciej, et al.
Publicado: (2018)

Cancer Drug Delivery: Considerations in the Rational Design of Nanosized Bioconjugates
por: Kobayashi, Hisataka, et al.
Publicado: (2014)

Recent Progress in Bioconjugation Strategies for Liposome-Mediated Drug Delivery
por: Almeida, Bethany, et al.
Publicado: (2020)

Synthesis of Lasalocid-Based Bioconjugates and Evaluation of Their Anticancer Activity
por: Antoszczak, Michał, et al.
Publicado: (2022)

Peptide-Based Bioconjugates and Therapeutics for Targeted Anticancer Therapy
por: Yang, Seong-Bin, et al.
Publicado: (2022)

Selection of a novel DNA aptamer against OFA/iLRP for targeted delivery of doxorubicin to AML cells
por: An, Yacong, et al.
Publicado: (2019)

Extracellular biosynthesis of gadolinium oxide (Gd(2)O(3)) nanoparticles, their biodistribution and bioconjugation with the chemically modified anticancer drug taxol
por: Khan, Shadab Ali, et al.
Publicado: (2014)

Novel Complex of PD-L1 Aptamer and Albumin Enhances Antitumor Efficacy In Vivo
por: An, Yacong, et al.
Publicado: (2022)

Aluminum nanoparticles enhance anticancer immune response induced by tumor cell vaccine
por: Sun, Zhao, et al.
Publicado: (2010)

Therapeutic aptamers: developmental potential as anticancer drugs
por: Lee, Ji Won, et al.
Publicado: (2015)

A ruthenium–oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy
por: McKenzie, Luke K., et al.
Publicado: (2021)

Novel HER2 Aptamer Selectively Delivers Cytotoxic Drug to HER2-positive Breast Cancer Cells in Vitro
por: Liu, Zhe, et al.
Publicado: (2012)

A Dual Bioconjugated Virus-Like Nanoparticle as a Drug Delivery System and Comparison with a pH-Responsive Delivery System
por: Biabanikhankahdani, Roya, et al.
Publicado: (2018)

Brain Delivery of Multifunctional Dendrimer Protein Bioconjugates
por: Moscariello, Pierpaolo, et al.
Publicado: (2018)

Pullulan Based Bioconjugates for Ocular Dexamethasone Delivery
por: Kicková, Eva, et al.
Publicado: (2021)

Novel Complex of PD-L1 Aptamer and Holliday Junction Enhances Antitumor Efficacy in Vivo
por: Li, Ting, et al.
Publicado: (2021)

Co-Opting Host Receptors for Targeted Delivery of Bioconjugates—From Drugs to Bugs
por: Tummillo, Kristen M., et al.
Publicado: (2021)

A Ligand‐Directed Nitrophenol Carbonate for Transient in situ Bioconjugation and Drug Delivery
por: Burt, Anthony J., et al.
Publicado: (2020)

Development of anti-MUC1 DNA aptamers for the imaging and radiotherapy of breast cancer
por: Da Pieve, C, et al.
Publicado: (2006)

Development of anti-MUC1 DNA aptamers for the imaging and radiotherapy of breast cancer
por: Da Pieve, C, et al.
Publicado: (2008)

Aptamers for Targeted Drug Delivery
por: Ray, Partha, et al.
Publicado: (2010)

Aptamer-Functionalized Gold Nanoparticles for Drug Delivery to Gynecological Carcinoma Cells
por: Lopes-Nunes, Jessica, et al.
Publicado: (2021)

Evolution of complexity in non-viral oligonucleotide delivery systems: from gymnotic delivery through bioconjugates to biomimetic nanoparticles
por: Bakowski, Kamil, et al.
Publicado: (2022)

Hydroxycamptothecin-loaded nanoparticles enhance target drug delivery and anticancer effect
por: Wang, Anxun, et al.
Publicado: (2008)

Employing defined bioconjugates to generate chemically functionalised gold nanoparticles for in vitro diagnostic applications
por: Richards, Daniel A., et al.
Publicado: (2021)

The Importance of Poly(ethylene glycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation
por: Hoang Thi, Thai Thanh, et al.
Publicado: (2020)

Carboxymethyl Hyaluronan-Stabilized Nanoparticles for Anticancer Drug Delivery
por: Woodman, Jessica L., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_7c6oldaits8cinkcl88a5p6h8q