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Expression and cellular localization of microRNA-29b and RAX, an activator of the RNA-dependent protein kinase (PKR), in the retina of streptozotocin-induced diabetic rats

PURPOSE: The apoptosis of retinal neurons plays a critical role in the pathogenesis of diabetic retinopathy (DR), but the molecular mechanisms underlying this phenomenon remain unclear. The purpose of this study was to investigate the cellular localization and the expression of microRNA-29b (miR-29b...

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Detalles Bibliográficos
Autores principales: Silva, Viviane A. O., Polesskaya, Anna, Sousa, Thaís A., Corrêa, Vani M. A., André, Nayara Delgado, Reis, Rosana I., Kettelhut, Isis C., Harel-Bellan, Annick, De Lucca, Fernando L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164688/
https://www.ncbi.nlm.nih.gov/pubmed/21897745