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An Iterative Genetic and Dynamical Modelling Approach Identifies Novel Features of the Gene Regulatory Network Underlying Melanocyte Development

The mechanisms generating stably differentiated cell-types from multipotent precursors are key to understanding normal development and have implications for treatment of cancer and the therapeutic use of stem cells. Pigment cells are a major derivative of neural crest stem cells and a key model cell...

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Detalles Bibliográficos
Autores principales: Greenhill, Emma R., Rocco, Andrea, Vibert, Laura, Nikaido, Masataka, Kelsh, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164703/
https://www.ncbi.nlm.nih.gov/pubmed/21909283
http://dx.doi.org/10.1371/journal.pgen.1002265