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Oxidation of Hepatic Carnitine Palmitoyl Transferase-I (CPT-I) Impairs Fatty Acid Beta-Oxidation in Rats Fed a Methionine-Choline Deficient Diet

There is growing evidence that mitochondrial dysfunction, and more specifically fatty acid β-oxidation impairment, is involved in the pathophysiology of non-alcoholic steatohepatitis (NASH). The goal of the present study was to achieve more understanding on the modification/s of carnitinepalmitoyltr...

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Detalles Bibliográficos
Autores principales: Serviddio, Gaetano, Giudetti, Anna M., Bellanti, Francesco, Priore, Paola, Rollo, Tiziana, Tamborra, Rosanna, Siculella, Luisa, Vendemiale, Gianluigi, Altomare, Emanuele, Gnoni, Gabriele V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164715/
https://www.ncbi.nlm.nih.gov/pubmed/21909411
http://dx.doi.org/10.1371/journal.pone.0024084