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PP1A-Mediated Dephosphorylation Positively Regulates YAP2 Activity
BACKGROUND: The Hippo/MST1 signaling pathway plays an important role in the regulation of cell proliferation and apoptosis. As a major downstream target of the Hippo/MST1 pathway, YAP2 (Yes-associated protein 2) functions as a transcriptional cofactor that has been implicated in many biological proc...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164728/ https://www.ncbi.nlm.nih.gov/pubmed/21909427 http://dx.doi.org/10.1371/journal.pone.0024288 |