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PP1A-Mediated Dephosphorylation Positively Regulates YAP2 Activity

BACKGROUND: The Hippo/MST1 signaling pathway plays an important role in the regulation of cell proliferation and apoptosis. As a major downstream target of the Hippo/MST1 pathway, YAP2 (Yes-associated protein 2) functions as a transcriptional cofactor that has been implicated in many biological proc...

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Detalles Bibliográficos
Autores principales: Wang, Pei, Bai, Yujie, Song, Bangrong, Wang, Yadong, Liu, Dong, Lai, Yongqiang, Bi, Xiaolin, Yuan, Zengqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164728/
https://www.ncbi.nlm.nih.gov/pubmed/21909427
http://dx.doi.org/10.1371/journal.pone.0024288