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Harmonin inhibits presynaptic Ca(v)1.3 Ca(2+) channels in mouse inner hair cells
Harmonin is a scaffolding protein required for normal mechanosensory function in hair cells. Here, we describe a novel presynaptic association of harmonin and Ca(v)1.3 Ca(2+) channels at the mouse inner hair cell synapse, which limits channel availability through a ubiquitin-dependent pathway.
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164920/ https://www.ncbi.nlm.nih.gov/pubmed/21822269 http://dx.doi.org/10.1038/nn.2895 |