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ABCG2 is a Direct Transcriptional Target of Hedgehog Signaling and Involved in Stroma-Induced Drug Tolerance in Diffuse Large B-Cell Lymphoma

Successful treatment of diffuse large B-cell lymphoma (DLBCL) is frequently hindered by development of resistance to conventional chemotherapy resulting in disease relapse and high mortality. High expression of anti-apoptotic and/or drug transporter proteins induced by oncogenic signaling pathways h...

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Detalles Bibliográficos
Autores principales: Singh, Rajesh R, Kunkalla, Kranthi, Qu, Changju, Schlette, Ellen, Neelapu, Sattva S, Samaniego, Felipe, Vega, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165099/
https://www.ncbi.nlm.nih.gov/pubmed/21625222
http://dx.doi.org/10.1038/onc.2011.195