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EPLIN Downregulation Promotes Epithelial-Mesenchymal Transition in Prostate Cancer Cells and Correlates With Clinical Lymph Node Metastasis

Epithelial-mesenchymal transition (EMT) is a crucial mechanism for the acquisition of migratory and invasive capabilities by epithelial cancer cells. By conducting quantitative proteomics in experimental models of human prostate cancer (PCa) metastasis, we observed strikingly decreased expression of...

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Detalles Bibliográficos
Autores principales: Zhang, Shumin, Wang, Xu, Osunkoya, Adeboye O., Iqbal, Shareen, Chen, Zhuo, Müller, Susan, Chen, Zhengjia, Josson, Sajni, Coleman, Ilsa M., Nelson, Peter S., Wang, Yongqiang A., Wang, Ruoxiang, Shin, Dong M., Marshall, Fray F., Kucuk, Omer, Chung, Leland W. K., Zhau, Haiyen E., Wu, Daqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165108/
https://www.ncbi.nlm.nih.gov/pubmed/21625216
http://dx.doi.org/10.1038/onc.2011.199